Novel Drug Delivery Systems I - M.Pharm 2nd Semester Supplementary Feb 2014

M.Pharm II Semester Supplementary Examinations, February 2014
NOVEL DRUG DELIVERY SYSTEMS I
(For students admitted in 2009, 2010 & 2011 only)
(Pharmaceutics)

Time: 3 hours                                                                                          Max Marks: 60
Answer any FIVE questions
All questions carry equal marks
1. Explain various factors effecting permeation of drug through skin. Explain various types of transdermal drug delivery systems designs.


2. (a) Explain the factors that should be considered while selecting a drug candidate for gastro retentive drug delivery system. Explain gas generating systems.

(b) Explain vesicular carriers for drug targeting.


3. (a) Write a note on monoclonal antibodies.

(b) Explain various components of osmotic drug delivery systems.


4. (a) Explain mechanism of permeation through mucosa.

(b) Write a note biodegradable systems,


5. (a) Give formulation of fast dissolving tablet.

(b) Write a note on ocusserts


6. (a) Give general methods for Analysis of proteins and peptide drugs.

(b) Explain preformulation for peptide drug delivery systems


7. (a) Explain lontophoresis as transdermal drug delivery system.

(b) Explain ex-vivo method for evaluation of mucoadhesive drug delivery system.


8. (a) Explain uses of ion exchange resins in drug delivery systems with example.

(b) Explain stability evaluation of peptide drug delivery systems.